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Johns Hopkins Children's Center

Baltimore, Maryland, United States
Children's hospital in Baltimore, Maryland
1800 Orleans St, Baltimore, MD 21287

About Johns Hopkins Children's Center


"Johns Hopkins Children’s Center brings the collaborative multidisciplinary might and expertise of this venerable institution to bear in treating every child who comes through its doors."
  • Top Sponsors
  • Top Collaborators
  • Trials By Phase
  • Recruitment Status
  • Top Conditions
  • Intervention Types
  • Top Intervention Names
  • Trials By Gender
Lead Sponsor
# Trials
National Institute of Allergy and Infectious Diseases (NIAID)
22
Johns Hopkins University
7
Genzyme, a Sanofi Company
2
PTC Therapeutics
2
University of Pennsylvania
2
University of Utah
2
Albireo
1
Baylor College of Medicine
1
Children's Hospital of Philadelphia
1
Connecticut Children's Medical Center
1
Emory University
1
Total Rows: 21

Clinical Trials at Johns Hopkins Children's Center


During the past decade, Johns Hopkins Children's Center conducted 12 clinical trials. In the 10-year time frame, 12 clinical trials started and 10 clinical trials were completed, i.e. on average, 83.3% percent of trials that started reached the finish line to date. In the past 5 years, 6 clinical trials started and 6 clinical trials were completed. i.e. 100% of trials that started reached the finish line.
Created with Highcharts 11.1.0TrialsTrials Trend - Last 10 Years2200110033551100111111116600Started TrialsCompleted Trails201520162017201820192020202102468
Trials List
Trail ID
Brief Title
Start Date
Completion Date
Status
Enrollment
A Randomized Comparative Trial of Zidovudine (AZT) Versus 2',3'-Dideoxyinosine (ddI) Versus AZT Plus ddI in Symptomatic HIV-Infected Children
1996-09-01
Completed
819
A Multicenter Trial To Evaluate Oral Retrovir in the Treatment of Children With Symptomatic HIV Infection
Completed
70
A Phase III Randomized, Double-Blind, Controlled Study of the Use of Anti-HIV Immune Serum Globulin (HIVIG) for the Prevention of Maternal-Fetal HIV Transmission in Pregnant Women and Newborns Receiving Zidovudine (AZT)
2007-08-01
Completed
1,600
A Study to Compare Different Drugs Used to Prevent Serious Bacterial Infections in HIV-Positive Children
2001-11-01
Completed
690
A Comparative Study of Combination Antiretroviral Therapy in Children and Adolescents With Advanced HIV Disease
1998-11-01
Completed
390
Study of Perinatal Transmission of Zidovudine-Resistant HIV Among Pregnant Women Treated With Zidovudine
Completed
250
The Safety and Effectiveness of Adefovir Dipivoxil in HIV-Infected Children
Completed
24
A Study of Nevirapine for the Prevention of HIV Transmission From Mothers to Their Babies
2001-05-01
Completed
2,009

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Clinical Trials Sponsors and Collaborators


Out of the total clinical trials conducted in "Johns Hopkins Children's Center" #1 sponsor was "National Institute of Allergy and Infectious Diseases (NIAID)" with 22 trials, followed by "Johns Hopkins University" with 7 trials sponsored, "Genzyme, a Sanofi Company" with 2 trials sponsored, "PTC Therapeutics" with 2 trials sponsored and "University of Pennsylvania" with 2 trials sponsored. Other sponsors include 12 different institutions and companies that sponsored additional 21 trials in total.
In terms of collaborators to trials, out of the total clinical trials conducted in "Johns Hopkins Children's Center" #1 collaborator was "Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)" with 10 trials as a collaborator, "Glaxo Wellcome" with 6 trials as a collaborator, "Johns Hopkins University" with 4 trials as a collaborator, "Baylor College of Medicine" with 3 trials as a collaborator and "Children's Hospital Los Angeles" with 3 trials as a collaborator. Other collaborators include 99 different institutions and companies that were collaborators in the rest 87 trials.
Created with Highcharts 11.1.0Top Leading SponsorsNational Institute ofAllergy and InfectiousDiseases (NIAID): 22National Institute ofAllergy and InfectiousDiseases (NIAID): 22Johns Hopkins University: 7Johns Hopkins University: 7Genzyme, a Sanofi Company: 2Genzyme, a Sanofi Company: 2PTC Therapeutics: 2PTC Therapeutics: 2University of Pennsylvania: 2University of Pennsylvania: 2University of Utah: 2University of Utah: 2Albireo: 1Albireo: 1Baylor College of Medicine: 1Baylor College of Medicine: 1Children's Hospital ofPhiladelphia: 1Children's Hospital ofPhiladelphia: 1Connecticut Children'sMedical Center: 1Connecticut Children'sMedical Center: 1

Created with Highcharts 11.1.0Top CollaboratorsEunice Kennedy ShriverNational Institute ofChild Health and HumanDevelopment (NICHD):10Eunice Kennedy ShriverNational Institute ofChild Health and HumanDevelopment (NICHD):10Glaxo Wellcome: 6Glaxo Wellcome: 6Johns Hopkins University: 4Johns Hopkins University: 4Baylor College of Medicine: 3Baylor College of Medicine: 3Children's Hospital LosAngeles: 3Children's Hospital LosAngeles: 3Nationwide Children's Hospital: 3Nationwide Children's Hospital: 3University of Pittsburgh: 3University of Pittsburgh: 3Ann & Robert H LurieChildren's Hospital ofChicago: 2Ann & Robert H LurieChildren's Hospital ofChicago: 2Arnold Palmer Hospitalfor Children: 2Arnold Palmer Hospitalfor Children: 2Bristol-Myers Squibb: 2Bristol-Myers Squibb: 2

Clinical Trials Conditions at Johns Hopkins Children's Center


According to Clinical.Site data, the most researched conditions in "Johns Hopkins Children's Center" are "HIV Infections" (23 trials), "Pregnancy" (5 trials), "Cardiac Arrest" (2 trials), "Cystic Fibrosis" (2 trials) and "HIV Seronegativity" (2 trials). Many other conditions were trialed in "Johns Hopkins Children's Center" in a lesser frequency.

Clinical Trials Intervention Types at Johns Hopkins Children's Center


Most popular intervention types in "Johns Hopkins Children's Center" are "Drug" (27 trials), "Other" (6 trials), "Behavioral" (4 trials), "Device" (4 trials) and "Procedure" (4 trials). Other intervention types were less common.
The name of intervention was led by "Zidovudine" (10 trials), "Nevirapine" (7 trials), "Didanosine" (6 trials), "Lamivudine" (4 trials) and "Nelfinavir mesylate" (4 trials). Other intervention names were less common.

Clinical Trials Genders at Johns Hopkins Children's Center


The vast majority of trials in "Johns Hopkins Children's Center" are 48 trials for "All" genders and 4 trials for "Female" genders.

Clinical Trials Status at Johns Hopkins Children's Center


Currently, there are NaN active trials in "Johns Hopkins Children's Center". undefined are not yet recruiting, 5 are recruiting, 1 are Active, not recruiting, and 1 are Enrolling by invitation. In total, there were 42 completed trials in Johns Hopkins Children's Center, undefined suspended trials, and 2 terminated clinical trials to date.
Out of the total trials that were conducted in Johns Hopkins Children's Center, 6 "Phase 1" clinical trials were conducted, 9 "Phase 2" clinical trials and 15 "Phase 3" clinical trials were conducted as well. "Phase 4" trials included 1 trials, and there were also 9 trials that are defined as “Not Applicable".
Created with Highcharts 11.1.0Trials By PhasePhase 3: 15Phase 3: 15Not Applicable: 9Not Applicable: 9Phase 2: 9Phase 2: 9Phase 1: 6Phase 1: 6Phase 4: 1Phase 4: 1

Created with Highcharts 11.1.0Trials StatusCompleted: 42Completed: 42Recruiting: 5Recruiting: 5Terminated: 2Terminated: 2Active, not recruiting: 1Active, not recruiting: 1Enrolling by invitation: 1Enrolling by invitation: 1Unknown status: 1Unknown status: 1