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Institut Jérome Lejeune

Paris, France
Research foundation in Paris
37 Rue des Volontaires, 75015 Paris

About Institut Jérome Lejeune


"En 1959, le Professeur Jérôme Lejeune, médecin et chercheur, a découvert l’origine génétique de la trisomie 21. A sa suite, la Fondation Jérôme Lejeune, reconnue d’utilité publique depuis 1996, agit pour les personnes atteintes de maladie génétique de l’intelligence (trisomie 21 , Williams-Beuren, X-fragile, maladie du cri du chat, autres trisomies, monosomies, retards mentaux inexpliqués…), en recevant avec l'Institut Jérôme Lejeune près de 10 000 patients tous les ans et en finançant de nombreux programmes de recherches scientifiques."
  • Top Sponsors
  • Top Collaborators
  • Trials By Phase
  • Recruitment Status
  • Top Conditions
  • Intervention Types
  • Top Intervention Names
  • Trials By Gender
Lead Sponsor
# Trials

Clinical Trials at Institut Jérome Lejeune


During the past decade, Institut Jérome Lejeune conducted 3 clinical trials. In the 10-year time frame, 3 clinical trials started and 1 clinical trials were completed, i.e. on average, 33.3% percent of trials that started reached the finish line to date. In the past 5 years, 1 clinical trials started and 1 clinical trials were completed. i.e. 100% of trials that started reached the finish line.
Created with Highcharts 11.1.0TrialsTrials Trend - Last 10 Years11001100110000001100Started TrialsCompleted Trails2017201820192020202100.511.5
Trials List
Trail ID
Brief Title
Start Date
Completion Date
Status
Enrollment
Efficacy Study of Folinic Acid to Improve Mental Development of Children With Down Syndrome
2000-10-01
2003-12-01
Completed
120
Down Syndrome and Continuous Positive Pressure Therapy
2006-11-16
2012-12-31
Completed
31
Correlations Phenotype / Genotype in Down Syndrome
2004-03-01
2011-05-01
Completed
524
Pilot Study of Auto-immune Abnormalities Associated With Down Syndrome
2009-11-01
2010-12-01
Completed
72
Efficacy Assessment of Systematic Treatment With Folinic Acid and Thyroid Hormone on Psychomotor Development of Down Syndrome Young Children
2012-04-02
2017-12-14
Completed
175
Early Detection and Treatment of Respiratory Sleep Disorders in Children With Down Syndrome
2017-07-31
2024-06-30
Active, not recruiting
80
Cohort Study of Adult Patients With Down Syndrome at Risk of Developing Alzheimer's Disease (TriAL21)
2019-04-26
2023-03-31
Recruiting
200
Trial-Ready Cohort-Down Syndrome (TRC-DS)
2021-06-07
2025-12-01
Recruiting
120

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Clinical Trials Sponsors and Collaborators


In terms of collaborators to trials, out of the total clinical trials conducted in "Institut Jérome Lejeune" #1 collaborator was "Fondation Jérôme Lejeune" with 4 trials as a collaborator, "Alzheimer's Clinical Trials Consortium" with 1 trials as a collaborator, "Alzheimer's Therapeutic Research Institute" with 1 trials as a collaborator, "Central Hospital, Nancy, France" with 1 trials as a collaborator and "Hôpital Cochin" with 1 trials as a collaborator. Other collaborators include -3 different institutions and companies that were collaborators in the rest 7 trials.
Created with Highcharts 11.1.0Top Leading SponsorsInstitut Jerome Lejeune: 7Institut Jerome Lejeune: 7University of SouthernCalifornia: 1University of SouthernCalifornia: 1

Created with Highcharts 11.1.0Top CollaboratorsFondation Jérôme Lejeune: 4Fondation Jérôme Lejeune: 4Alzheimer's ClinicalTrials Consortium: 1Alzheimer's ClinicalTrials Consortium: 1Alzheimer's TherapeuticResearch Institute: 1Alzheimer's TherapeuticResearch Institute: 1Central Hospital, Nancy,France: 1Central Hospital, Nancy,France: 1Hôpital Cochin: 1Hôpital Cochin: 1Hôpital Necker-EnfantsMalades: 1Hôpital Necker-EnfantsMalades: 1National Institute onAging (NIA): 1National Institute onAging (NIA): 1

Clinical Trials Conditions at Institut Jérome Lejeune


According to Clinical.Site data, the most researched conditions in "Institut Jérome Lejeune" are "Down Syndrome" (7 trials), "Alzheimer Disease" (2 trials), "Dementia" (1 trials), "Down Syndrome With and Without Auto Immune Abnormalities" (1 trials) and "Obstructive Sleep Apnea Syndrome" (1 trials). Many other conditions were trialed in "Institut Jérome Lejeune" in a lesser frequency.

Clinical Trials Intervention Types at Institut Jérome Lejeune


Most popular intervention types in "Institut Jérome Lejeune" are "Drug" (2 trials), "Device" (1 trials), "Diagnostic Test" (1 trials), "Procedure" (1 trials) and "Radiation" (1 trials). Other intervention types were less common.
The name of intervention was led by "Continuous Positive Pressure" (1 trials), "Flutafuranol" (1 trials), "MK6240" (1 trials), "Neuro-imaging, Lumbar puncture" (1 trials) and "Pittsburgh Compound (PIB)" (1 trials). Other intervention names were less common.

Clinical Trials Genders at Institut Jérome Lejeune


The vast majority of trials in "Institut Jérome Lejeune" are 8 trials for "All" genders.

Clinical Trials Status at Institut Jérome Lejeune


Currently, there are NaN active trials in "Institut Jérome Lejeune". undefined are not yet recruiting, 2 are recruiting, 1 are Active, not recruiting, and undefined are Enrolling by invitation. In total, there were 5 completed trials in Institut Jérome Lejeune, undefined suspended trials, and undefined terminated clinical trials to date.
Out of the total trials that were conducted in Institut Jérome Lejeune, 0 "Phase 1" clinical trials were conducted, 1 "Phase 2" clinical trials and 2 "Phase 3" clinical trials were conducted as well. "Phase 4" trials included 0 trials, and there were also 3 trials that are defined as “Not Applicable".
Created with Highcharts 11.1.0Trials By PhaseNot Applicable: 3Not Applicable: 3Phase 3: 2Phase 3: 2Phase 2: 1Phase 2: 1

Created with Highcharts 11.1.0Trials StatusCompleted: 5Completed: 5Recruiting: 2Recruiting: 2Active, not recruiting: 1Active, not recruiting: 1