"L' Istituto Neurologico "Carlo Besta" è un polo di eccellenza per la ricerca e la cura delle più significative malattie neurologiche. Il Besta coniuga in modo sinergico le attività di ricerca scientifica, di diagnosi e cura – che danno origine ad un continuo miglioramento dell’efficacia terapeutica – nell’ambito della neurologica clinica e di base e si occupa dei disturbi neurologici dell’adulto e del bambino, delle patologie neurochirurgiche ed oncologiche, delle malattie croniche e rare."

During the past decade, Fondazione IRCCS Istituto Neurologico Carlo Besta conducted 79 clinical trials. In the 10-year time frame, 79 clinical trials started and 18 clinical trials were completed, i.e. on average, 22.8% percent of trials that started reached the finish line to date. In the past 5 years, 38 clinical trials started and 12 clinical trials were completed. i.e. 31.6% of trials that started reached the finish line.

Out of the total clinical trials conducted in "Fondazione IRCCS Istituto Neurologico Carlo Besta" #1 sponsor was "Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta" with 19 trials, followed by "Eli Lilly and Company" with 6 trials sponsored, "Hoffmann-La Roche" with 5 trials sponsored, "Amgen" with 4 trials sponsored and "European Organisation for Research and Treatment of Cancer - EORTC" with 4 trials sponsored. Other sponsors include 67 different institutions and companies that sponsored additional 62 trials in total.

In terms of collaborators to trials, out of the total clinical trials conducted in "Fondazione IRCCS Istituto Neurologico Carlo Besta" #1 collaborator was "Cedars-Sinai Medical Center" with 3 trials as a collaborator, "Children's Hospital of Philadelphia" with 3 trials as a collaborator, "Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta" with 3 trials as a collaborator, "Johns Hopkins University" with 3 trials as a collaborator and "Stanford University" with 3 trials as a collaborator. Other collaborators include 83 different institutions and companies that were collaborators in the rest 73 trials.

According to Clinical.Site data, the most researched conditions in "Fondazione IRCCS Istituto Neurologico Carlo Besta" are "Glioblastoma" (9 trials), "Migraine" (8 trials), "Glioblastoma Multiforme" (5 trials), "Alzheimer Disease" (4 trials) and "Alzheimer's Disease" (4 trials). Many other conditions were trialed in "Fondazione IRCCS Istituto Neurologico Carlo Besta" in a lesser frequency.

Most popular intervention types in "Fondazione IRCCS Istituto Neurologico Carlo Besta" are "Drug" (70 trials), "Device" (11 trials), "Other" (11 trials), "Behavioral" (7 trials) and "Radiation" (7 trials). Other intervention types were less common.

The name of intervention was led by "Placebo" (30 trials), "Temozolomide" (5 trials), "Bevacizumab" (4 trials), "Lomustine" (4 trials) and "placebo" (4 trials). Other intervention names were less common.

The vast majority of trials in "Fondazione IRCCS Istituto Neurologico Carlo Besta" are 107 trials for "All" genders and 3 trials for "Male" genders.

Currently, there are 50 active trials in "Fondazione IRCCS Istituto Neurologico Carlo Besta". 1 are not yet recruiting, 37 are recruiting, 11 are Active, not recruiting, and 1 are Enrolling by invitation. In total, there were 38 completed trials in Fondazione IRCCS Istituto Neurologico Carlo Besta, undefined suspended trials, and 10 terminated clinical trials to date.

Out of the total trials that were conducted in Fondazione IRCCS Istituto Neurologico Carlo Besta, 7 "Phase 1" clinical trials were conducted, 28 "Phase 2" clinical trials and 37 "Phase 3" clinical trials were conducted as well. "Phase 4" trials included 6 trials, and there were also 14 trials that are defined as “Not Applicable".

Fondazione IRCCS Istituto Neurologico Carlo Besta has several departments that took part in Clinical trials: "Fond. Istituto Neurologico C.Besta; UO Neurologia IV - Neuroimmunologia Malattie Neuromuscolari" - 9 trials, "Fondazione IRCCS Istituto Neurologico "Carlo Besta"; UO di Neurologia dello Sviluppo" - 3 trials, "Fondazione IRCCS Istituto Neurologico Carlo Besta; U.O.C. Genetica Medica-Neurogenetica" - 2 trials